The 2025 NFL Week 2 odds are out. There are 16 video games this week. These embody: NFL a Tremendous Bowl rematch, divisional battles, and video games that would sign early contenders. The video games begin Thursday, September eleventh, with the Washington Commanders going through the Inexperienced Bay Packers, and wraps up with a Monday Night time Soccer doubleheader on September fifteenth. Betting strains have shifted primarily based on Week 1 outcomes, reflecting accidents, surprises, and workforce changes.Â
As at all times, these odds are notional and topic to vary—keep in mind, that is for informational functions solely and never meant as monetary or betting recommendation. Guess responsibly and benefit from the video games!
NFL Week 2 Highlighted Video games
Listed below are 4 key matchups from Week 2, that includes tight strains, high-profile rematches, and potential for some enjoyable like we had in week1.Â
Philadelphia Eagles at Kansas Metropolis Chiefs (Sunday, Sept. 14, 4:25 p.m. ET): In a rematch of Tremendous Bowl LIX, the Eagles open as slight street favorites towards the defending champions. With an expansion of Eagles -1.5, moneyline of Eagles -120 / Chiefs +100, and an over/beneath of 46.5, this sport could possibly be a shootout between two elite offenses led by Jalen Hurts and Patrick Mahomes.
Buffalo Payments at New York Jets (Sunday, Sept. 14, 1 p.m. ET): This AFC East rivalry pits Josh Allen’s Payments towards Aaron Rodgers and the Jets. Buffalo is favored by 6.5 factors, with a moneyline of Payments -320 / Jets +260 and an over/beneath of 46.5.Â
Cleveland Browns at Baltimore Ravens (Sunday, Sept. 14, 1 p.m. ET): The Ravens, coming off a powerful Week 1, are heavy favorites on this AFC North conflict. Unfold sits at Ravens -11.5, moneyline Ravens -900 / Browns +550, and over/beneath 44.5. Lamar Jackson’s squad seems to dominate, however Cleveland’s protection might preserve it nearer.
Chicago Bears at Detroit Lions (Sunday, Sept. 14, 1 p.m. ET): NFC North foes collide because the up-and-coming Bears go to the Lions. Detroit is favored by 5.5 factors, with a moneyline of Lions -250 / Bears +210 and an over/beneath of 47.5. This could possibly be a high-scoring affair with younger quarterbacks Caleb Williams and Jared Goff beneath the highlight.
Different shut contests to look at embody the Chargers at Raiders and Falcons at Vikings, the place strains counsel shut video games.Â
2025 NFL Week 2Odds Desk
Right here’s the 2025 NFL Week 2 odds desk for you. It consists of the unfold, moneyline, and over/beneath for the sport. You can too checkout our Week 2 pick-em sheet that doesn’t embody the chances right here for the video games. (odds through consensus from main sportsbooks like ESPN and FOX Sports activities):
| Away @ House | Unfold | Moneyline | Over/Underneath |
| Commanders @ Packers | Packers -3.5 | Packers -185 / Commanders +155 | 48.5 |
| Jaguars @ Bengals | Bengals -3.5 | Bengals -185 / Jaguars +155 | 48.5 |
| Giants @ Cowboys | Cowboys -5.5 | Cowboys -260 / Giants +215 | 44.5 |
| Bears @ Lions | Lions -5.5 | Lions -250 / Bears +210 | 47.5 |
| Rams @ Titans | Rams -5.5 | Rams -260 / Titans +215 | 41.5 |
| Patriots @ Dolphins | Dolphins -1.5 | Dolphins -120 / Patriots +100 | 42.5 |
| 49ers @ Saints | 49ers -4.5 | 49ers -230 / Saints +195 | 42.5 |
| Payments @ Jets | Payments -6.5 | Payments -320 / Jets +260 | 46.5 |
| Seahawks @ Steelers | Steelers -2.5 | Steelers -150 / Seahawks +130 | 39.5 |
| Browns @ Ravens | Ravens -11.5 | Ravens -900 / Browns +550 | 44.5 |
| Broncos @ Colts | Broncos -1.5 | Broncos -130 / Colts +110 | 43.5 |
| Panthers @ Cardinals | Cardinals -6.5 | Cardinals -290 / Panthers +240 | 44.5 |
| Eagles @ Chiefs | Eagles -1.5 | Eagles -120 / Chiefs +100 | 46.5 |
| Falcons @ Vikings | Vikings -4.5 | Vikings -210 / Falcons +175 | 45.5 |
| Buccaneers @ Texans | Texans -2.5 | Texans -140 / Buccaneers +120 | 42.5 |
| Chargers @ Raiders | Chargers -3.5 | Chargers -185 / Raiders +155 | 47 |
2025 NFL Preseason and Common Season Schedules
We’ve got the entire 2025 NFL common season schedules posted so that you can get pleasure from. You can too checkout the entire particular person workforce schedules (Common Season) beneath in addition to the 2026 NFL Playoff bracket and Tremendous Bowl Schedule .
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